![]() Food and Drug Administration (FDA) as a non-controlled analgesic. In 1995, tramadol was originally approved by the U.S. In addition to acting at the opioid pain receptor, tramadol also inhibits uptake of two neurotransmitters, norepinephrine and serotonin, which may add to its pain-relief effects, although the exact mechanism isn't exactly known. The safety and effectiveness of tramadol in children have not been established. Do not use more than one tramadol product at a time or exceed the dose prescribed by your doctor. The lowest effective dose for the shortest duration should be used. Tramadol is approved for the treatment of pain in adults that is severe enough to require an opioid analgesic and for which other treatments do not work or are not tolerated. Opioids have made headlines over the past few years due to the tremendous problem of opioid addiction in the U.S. Other opioids include drugs you may be more familiar with, like oxycodone or codeine. The facts: tramadol is classified as a centrally-acting, oral analgesic (pain drug) that contains an opioid (narcotic). But is that really true? Is tramadol a narcotic? Maybe you've heard that tramadol is a "safer" pain medication. Medically reviewed by Leigh Ann Anderson, PharmD. ![]()
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